Buy Unisom Online


Patients use Doxylamine Succinate as a blocker of histamine H1-receptors of the group ethanolamine. It has a sedative, hypnotic effect. The preparations shortens the time of falling asleep, increases the length and quality of sleep. It also has an anti-allergic effect.

The sedative effect of the preparation is comparable with barbiturates. The duration of its action is 6-8 hours.

Doxylamine is well absorbed in the gastrointestinal tract. It penetrates through the various tissue barriers, including the blood-brain barrier and distributed to organs and tissues. Doxylamine is metabolized in the liver. From the organism, the drug is excreted by the kidneys (and unchanged 60%), as well as Doxylamine is partially excreted with faeces.


Sleep disorders; itching; allergic reactions; cough and catarrhal diseases (in the combined drugs).

How to take

It is taken inside. Adults suffering from insomnia ought to take 15-25 mg for 15-30 minutes before sleep. In allergic reactions the dose is up to 25 mg every four-six hours

Children at age 6-12 – 6.25-12.5 mg every four-six hours.

The maximum dose for adults to take daily – 150 mg.

It is not recommended for drivers of vehicles during operation, and also people whose activity is connected with the high concentration of attention to use Doxylamine. At night take the preparation to take with caution, as it may cause dizziness or confusion. During the treatment it is necessary to stop using alcohol. Doxylamine contains 484 mg of sodium bicarbonate, and this fact must be considered by people following a low-salt diet.


The preparation has a strong effect but there are some people who can’t use Unisom. They include glaucoma, prostate cancer, lactation, children up to 6 years (as antihistamine funds), child and adolescence to 15 years (as a sedative-hypnotic), increased sensitivity to Doxylamine.

The restrictions include:

  • the diseases of the lungs.
  • necessity to avoid driving and other activities requiring rapid psychomotor reactions.

Side effects

There are some side effects that a patient can experience after you Doxylamine.

Possible side effects: weakness, drowsiness, dry mouth, constipation, urinary disturbances.


Before you use Doxylamine learn all the rules how to take the preparation and never take more than it is required.

The accidental or intentional overdosage is only possible when patients take high doses. In children the symptoms of intoxication are excitation, hallucinations, ataxia, loss of coordination, convulsions.

The symptoms occur sequentially, but in some cases the first symptoms of acute poisoning may be tremor.

Death due to intoxication may occur in a period of between 2 and 98 hours after the overdose.

Symptoms of acute poisoning in adults may differ: lethargy and coma sometimes occurs prior to the development convulsing and excitation; hyperthermia and redness of the skin. The treatment is symptomatic.

Drug interactions

With the simultaneous use of antidepressants, barbiturates, clonidine, opioid analgesics, neuroleptics, tranquilizers enhances a dampening effect of Doxylamine on the central nervous system.

Simultaneous administration of atropine means, imipramine, fenotiazina derivatives increased risk of anticholinergic side effects (dry mouth, constipation, the delay urination).

With the simultaneous use of ethanol Doxylamine sedative effect is enhanced.


Do not give this medicine to children who are under two years old. Always ask a doctor giving a cough or cold medicine to a child.

Use this drug, as indicated on the label, or as you were prescribed. Do not use the preparation in larger amounts or longer time than it is recommended.

Ask your doctor or pharmacist about taking this medicine if you suffer from glaucoma, an enlarged prostate, kidney disease, problems with urination, stomach ulcers or obstruction or chronic lung diseases such as emphysema and bronchitis.

If you miss a dose, take it just at the moment you remember. Better to take Doxylamine only when you can take a few hours for sleep. If it ihappens to be almost normal waking hour, patients can skip the missed Doxylamine dose and wait until you’re ready for bed. The use extra medicine to make up the missed dose is forbidden.

There may be other preparations that can’t interact with Doxylamine. Your health care provider should be informed about all your prescription and non-prescription medicines, minerals, vitamins, herbal products, and medicines prescribed by other specialists.